A vaccine against HIV and AIDS

HIV has become one of the most important problems of mankind. So many years, scientists and researchers are looking for a way to beat the disease by destroying the virus in the infected organism. More than once was presented to the HIV vaccine, which was tested. But some of them were a failure, as the HIV vaccine did not work or worked not. Still, scientists do not despair and try to get new opportunities in this field to invent new drugs. All complicated by the fact that the virus is simply embedded in the human genome. Therefore, invented a vaccine for AIDS should only work on the virus itself, without harming the person. But at the moment no vaccine against AIDS is not able to completely remove it from the body.

combat HIV

Attempt and search for different ways is still continuing. Ideas quite a lot, but to implement and test each of them so quickly fails. This takes time and money. Some scientists want to start from the possible production of antibodies to the virus, others say about the creation of a mutation of the CCR5 receptor. After all, his absence gives the virus the ability to attach to the body.

Vaccination against HIV

The meaning of HIV vaccination is the introduction into the human body a vaccine that has a virus. However, he changed enough that it is considered absolutely safe for the body. Its parameters are almost the same as the original virus, but the difference is that the human body begins to fight with him.

If I can develop a sufficient immune system's response to the HIV vaccine, and then in contact with this virus the body will have been prepared. In this case, he will develop antibodies to the copies spreading virus and cease its existence.

Modern development

Once found the virus, scientists immediately began to seek a method of destruction. For this was invented a lot of different drugs and vaccines. But not all of them were reliable. Therefore, studies are still ongoing. Because vaccine or medicine can produce in wide use. It takes years to explore, track and operate the experiment. But modern scientists have found several ways to affect the immunodeficiency.

Vaccine for production of antibodies

HIV vaccine tried to develop for many years. Last year a team of scientists led by Joseph Jardina found some people have the antigen that could be the basis for the vaccine. These people just produce antibodies that simply neutralize the rapidly mutating strains of the virus.

Therefore, scientists try to give the opportunity to the immune system of infected to see the virus and produce antibodies to it. So they are trying to teach a vaccine to help b-cells see the virus. Because HIV destroys T-lymphocytes, which are infiltrated any virus or bacteria. Therefore, the lymphocytes are not able to show In the cells in which the microorganism should be marked for destruction.

But since in natural conditions these antibodies in humans produced very little, scientists are trying to find all possibilities to receive the necessary amount of vaccine. They presented an article in which he described his first experiences and nanovaccines protein EOD-GT8 60mer, which helps to form antibodies against HIV.

Vaccination against HIV

A couple of years ago in new York were tested according to the invention the vaccine virus. Involved several people and the results pleased not only them, but also of the inventors. 8 of 9 people decreased viral load in hundreds of times.

Yet scientists do not tend to release the vaccine for public use. One of the researchers noticed that the necessary test some more, because maybe after some time, the virus may again start its spread throughout the body.

Research and invention of vaccines

Some countries have carried out trials of the vaccine AIDSVAX. It is based on the gp120 protein of the virus and has passed all clinical trials successfully. Therefore, scientists have the desire to continue and not to stop.

Academic institutions in the UK and Kenya have combined their efforts to research and have invented onefrom vaccines. At the moment it passes all preclinical tests to proceed to the next level and it could be tested on volunteers.

The organization IAVI, presented the project, which proposes to place a virus a bacterium of the genus Salmonella. While the bacterium to disarm. This vaccine will be a nasal spray, because Salmonella is very tenacious and survive well in saliva and in gastric juice. This may be a convenient method of delivering vaccines into the body.

Tests by US scientists

In one study, US scientists have pioneered a different way to use vaccines against HIV. They talk about genetic mutations of some muscle cells. This will create true advocates and they will be able to enter into the blood of special agents, able to inhibit the virus.

At the moment the tests were conducted only on monkeys. However, the researchers noted that the experiences were positive and these data allow us to give many infected hope for recovery.

Also, the US researchers carried out many tests with parts of Africa, where the incidence is quite high. The tests were conducted by ALVAC vaccine that produced a good immune response.

research in Russia

Research and development given the opportunity to invent a vaccine and to conduct the first clinical trials. The second stage gradually continues, but we can tell you about the excellent results.

The vaccine showed no side effects. While it has enabled the immune system to launch a necessary process for cellular and humoral response against HIV. After a full clinical trials of the vaccine will be represented among candidates on a global level.

Comprehensive protection

International Congress in Barcelona gave a comprehensive vaccine against hepatitis C and HIV. This new tool will be appropriate, because you can often find a combination of these diseases. However, they do not just exist together, but also exacerbate the human condition. And vaccination against them will help to forget about such a terrible disease.

The study was conducted on several groups of volunteers. Invented the drug showed excellent immune response. So scientists are talking about creating a healthy immune response to the penetration of the virus and disease in the body.

What prevents the development of the vaccine

All news about working on the invention of a vaccine is undoubtedly encouraging. Perhaps in the near time will be presented to one or more options. Yet the work is still ongoing, because to do everything is not so simple.

Researchers constantly find obstacles in the form of immune response. To give one hundred percent the forecast for the behavior of the immune system in a given situation is quite difficult. This is what slows down development and testing. Human immunity is so versatile and unique that to study it requires a lot of decades. While scientists are not even sure that they will be able to recognize all his secrets.

Therefore, behaviors of the immune system and its response to vaccines much more than you can imagine. How it will behave, no one knows. The same vaccine in different people is absolutely not the same. Therefore, scientists calculate and find out all the details. I want to create a drug that will suit absolutely everyone, and will not work selectively.

combat HIV

At the moment after a positive result on an HIV test, a person asks for help. Several decades ago there was a antiretroviral drugs. They are taken to suppress the virus, which helps to control its multiplication in the body. And the sooner you turn infected, the sooner treatment begins.

Thanks to such drugs, the virus simply "falls asleep", allowing the immune system to function normally. This greatly extends the life of a person, because earlier before the invention of these drugs are infected can live 10-12 years after infection. At the moment, with treatment, their life duration is not different from the average person.

It is important not to despair and time to go to the doctor. The longer this delay, the more difficult will be the treatment and you may not be able to achieve better results.

Side effects of antiretroviral therapy

All side effects from the drugs are divided into early and late. But actually all these unpleasant side cases can be removed. There are effects that simply require some time to getting used to. In this case, the person will feel nausea, possible allergic rash. But after a few weeks it goes away.

If we infected a hypersensitivity of the organism to the drug, it is natural that this would be an unpleasant side effect. In this case, simply replace the drug to a more suitable and all troubles are gone.

It is also important to understand that when a body is necessary to change the medication in order to avoid adverse effects. For example, this is done by reducing the hemoglobin.

Early treatment is often advisable to pay a visit to the doctor in time to pass the necessary tests. This allows the specialist to see the patient's condition and assess how well the valid prescription drug. It will also allow you to notice the deterioration or side effects.

If you do not apply the therapy against HIV

Atrefusal of treatment, a large proportion of infected to live more than 12 years. The rest can live a few years longer. There are cases where an unwillingness to be treated with antiretroviral drugs, claimed the life of patients for 3-5 years.

Life expectancy without treatment is largely dependent on the immune system and the aggressiveness of the virus. Than it will be larger the faster it spreads throughout the body. Also it depends on the infection. If the person is contracted from an AIDS patient, then of course the disease is in the accelerated form.

Gives some influence on the duration of the life of the age and state of health. If the person is older, the immunity he is weaker. The same applies to people with pathologies and other diseases. HIV progresses rapidly without treatment and in 99% of cases simply goes for a few years in the AIDS.

Therefore, it is important not to abandon treatment and to take prescribed medicines. Even when it seems easier not to quit the treatment. The remaining virus in the body will again begin to multiply, taking up a winning position. The antiretroviral drugs have to be permanent.