The scheme of treatment of herpes 1 and 2 type

Herpes simplex virus (Herpes simplex) causes recurrent skin infection with symptoms on mucous membranes and other organs. Timely local treatment of herpes speeds up healing, integrated treatment is used for immunosuppression, severe manifestations and frequent relapses. In the prevention is used to support cellular immunity or daily the preventive use of antiviral drugs.

Infection Herpes Simplex

Herpes simplex infections are caused by ubiquitous DNA virus HSV, their sole owner is solely. Viruses HSV, including Herpes zoster, relate to the group of alpha-herpesviruses. The herpes virus in respect to antigenic and biological characteristics are divided into 2 types – type HSV-1 (in most cases, is the causative agent of lesions of the tongue, oral cavity, lips and eyes) and HSV-2 (genital herpes, the causative agent of anogenital and neonatal infection; affects the genitals and sometimes the internal sex organs).

People have both types cause two types of infection: acute and chronic – latent, latent. Hence, like the name of the virus – herpein (Greek.: «creeping.)»

The body is first subjected to a primary infection. Its source is in direct contact with the secretions (mouth, genitals), active skin lesions and blood of an infected person. The virus attacks the cells of the damaged skin or mucous membranes with defective immune defense, as gateway uses the respiratory tract, the skin, the mucous membranes of the genital organs, penetrates through the placenta.

Primary infection with HSV-1 occurs in children aged 4 months to 3-5 years (60% of children up to age 5 years). Only 2-10% of children with clinically apparent infection, often manifest gingivostomatit or even a change in the General condition with fever, loss of appetite, fatigue, headache, sore throat or submandibular lymph nodes. The infection can spread to other places: example you can grant the herpes nails, neck, ears.

Primary HSV-1 infection can also occur in adolescents; manifestations include symptoms of pharyngitis, pharyngotonsillitis, infection of the lips, cheeks, nose or ear. Threatening infections caused by HSV-1 are keratoconjunctivitis, herpetic eczema, herpetic encephalitis.

Primary HSV-2 infection occurs in the period after the beginning of sexual activity at the age of 15 to 30 years. Are one of the most common sexually transmitted diseases. Manifested by sores in the genital area and perineum, associated with painful sensations, difficulty urinating, constipation, and swelling of inguinal lymph nodes. Threat is the primary infection with HSV-2 during pregnancy, 1 trimester, causing malformations of the fetus in the 2nd trimester is up to 50% risk of neonatal herpes because of the asymptomatic excretion of virus generic ways.

All about herpes viruses

Up to 90% of people in the body have a time bomb called the herpes virus. It is impossible to tell when they attack the body and manifest themselves in the form of unsightly and causing discomfort of rashes. It depends primarily on the condition of immunity, which, just after the winter weakened. Harm Solarium, Spa and social events which they can visit infected people.

Herpes simplex virus is a highly contagious infectious disease that mainly affects the skin and mucous membranes of the mouth, but can also manifest on the genitals, eyes and face. After the first infection, usually ages 1 to 5 years of life, the virus "lives" in nerve cells throughout life, most of the time survives without clinical symptoms like blisters or pimples, and waiting for his chance to manifest.

The causal factor of the disease can be represented by a weakened immune system, intense sun exposure, hypothermia, fever, poor nutrition, menstruation, emotional stress.

Transmission is possible with saliva, for example, when drinking from a shared bottle or by kissing, shared use of towels, Cutlery and so on. Also a possible way of infection is sexual contact.

How often are herpes rashes

Someone suffers from cold sores frequently, even every month, someone manifestations occur only 3 times a year. Cold sores on the lips (HSV-1) usually heal within 10 days. The situation worsens in the case,when the blisters it creates several. And not necessarily just on the lip, but anywhere on the face. In that case, if a blister occurs around the eyes, contact your doctor, as it can damage your eyesight. Never pierce a blister, because its content is very contagious./p>

To prevent precipitation, in particular, plays a big role in strengthening the immune system, the elimination of stress factors and a lot of exercise, protection from UV radiation (direct sunlight and Solarium).

Genital herpes

Even more unpleasant is genital herpes HSV-2 sexually transmitted diseases, which can infect even the hands or lips. Appears rash in the genital area and around the anus. Ulcers are very painful, the disease is often accompanied by fever, swollen lymph nodes, weakness and nausea.

Protection from infections is complex because the carrier can be a person who has no symptoms. The only reliable way of treatment and prevention presents sexual abstinence, monogamy, condom use. After the virus settles in the body, it cannot be immediately cured. In the case of infection genital herpes women before childbirth, this is the basis for a cesarean section, infection of the newborn involves danger to his life. In case of genital herpes, especially primary, consult a doctor.

To reduce itching will help a bath with oatmeal (a bowl of cereal soak in a little water, pour into the bath) or tea tree oil.

The virus in the body goes to sleep while strengthening the immune system.

Complex treatment of herpetic infections

Treatment of genital herpes in practice based on the use of the nucleosides and their analogues that block the function of DNA polymerase, and stops the reproduction of viral DNA. To activate the active substances necessary viral timidinkinaza; they are looking for selective cells infected with a virus, and does not affect healthy cells. In the treatment of primary infection in individuals with weakened immune systems, these drugs are taken for 7-10 days, in the case of a recurrent infection to 5 days.

The scheme of treatment of herpes in accordance with the nature of the lesions also based on the combination and the individual intake of certain medications.

Brivudin (Tostevin, tablets, 125 mg) is intended for the treatment of CMV infection, to some extent, is able to treat herpes simplex. Introduced within 5-10 days, 4 times a day 125 mg, people with renal insufficiency, the drug is contraindicated.

Acyclovir (Zovirax, Herpecin, tablet, 200 and 400 mg) is one of the most common drugs. Typical well tolerated, its side effects are light. The drug shows low bioavailability (about 20%) and mainly in unchanged form excreted in the urine (as a result, increases the side effects of nephrotoxic drugs). The half-life of Acyclovir is short – 2.5-3 hours. For daily chemoprophylaxis treatment of herpes is up to 6 months in a daily dose of 1 to 2 times 400 mg (mandatory monitoring of kidney function).

Valacyclovir (he needs therapy with valtrex, pills, 500 mg) – L-valine ester of acyclovir that is metabolized in the body into the active acyclovir. Valacyclovir shows the efficiency in all forms of Herpes simplex infection, it involves mainly the treatment of genital herpes and ocular.

Famciclovir (Famvir tablets, 125 mg) is a drug characterized by a high bioavailability of up to 75%.

The scheme of treatment of herpes in addition to the antiviral therapy includes the use of immunomodulators, normalizing violations of cellular immunity.

Local treatment of herpetic infections

Drugs that stop the penetration and the replication of the virus, it is best used at the prodromal stage labiales, genital or intraocular forms (later they are less effective); medications used 5 times a day every 4 hours with night break. The formulations are applied with a cotton swab on the localization of the for 4-5 days (max 10 days). Do not apply on mucous membranes or near the eyes, because the medication can cause burning, itching or redness at the application site on the skin.

1. Idoxuridine, Isopropyl-deoxyuridine, Trifluridine effects uncertain.
2. Acyclovir (5% – Zovirax, Herpecin, 3% for eye herpes – Zovirax) – prodromal labialis and genital herpes, herpetic keratitis (5 times a day for 7 days), minimal absorption.
3. Penciclovir (1% Vectavir) – contains in the infected tissue for up to 12 hours, reduces the excretion of virus after the appearance of papules and vesicles. Acute is used with a frequency of every 2 hours for 4 days.
4. Ganciclovir (Virgan gel 1.5 g/g) – treatment of acute herpetic keratitis – the application within 21 days.
5. Tromantadine (Viru-Merz gel 1%) – prevents the penetration of the virus at an early stage of replication.
6. Docosanol (10% Artaban) — prevents penetration of the virus into the cell.