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Analysis of cytomegalovirus transcript, normal levels

There are many viruses that can have a harmful effect on the human body. However, some can be in active and inactive phase. Analysis of cytomegalovirus is sufficient for the reason that CMV belongs to the family of herpes viruses is the most common in the modern world. For a long time, the PCR may be located in a latent form and does not manifest itself, however, in a difficult period, with a significant weakening of immunity, there is a probability of its activation and the manifestation of bright symptoms. Note that the agent quite often located in the tissues of the salivary glands – this determines the airborne method of transmission. Once the infection enters the body, it remains for life (it is known only a small number of cases decay the infection and its removal from the body).

Analiz na citomegalovirus rasshifrovka, normalnye pokazateli

Mode of transmission

There are several basic ways of transmission from one person to another:

  1. Airborne path is the most common method of transmission because of the characteristics of the localization of the pathogen.
  2. By close contact through saliva.
  3. Know quite a lot of cases, when transmitted sexually.
  4. Through blood transfusion, sharing of personal hygiene.
  5. Most dangerous situations can be called transmission of the virus from mother to fetus or newborn baby. Transmission can occur in utero, at birth and during breastfeeding.
Analiz na citomegalovirus rasshifrovka, normalnye pokazateli

The incubation period may range from several to 60 days. The most dangerous acute phase of the disease, which lasts for 2-6 weeks. The main symptoms can be called the appearance of weakness, high temperature, snobi, pain in the muscles. If symptoms persist you should visit a doctor who shall appoint a analysis for cytomegalovirus.

Indications for testing

Due to the fact that CMV in the blood may be no manifestation of symptoms and complications can lead to very serious consequences, doctors recommend to take responsibility for the problem — research on cytomegalovirus for certain situations on prescription. As a rule, the basis for detection of CMV be the following reasons:

  1. Planning pregnancy. Consider the class of the infection included in the group, which leads to the interruption of pregnancy under certain circumstances.
  2. With significantly compromised immunity or HIV.
  3. With the development of neoplastic disease.
  4. If the symptoms of intrauterine infection. Analysis of cytomegalovirus may show a positive result, that would cause a treatment or further tests.
  5. At the time of receiving cytotoxic drugs will also be assigned to a blood test for cytomegalovirus.
  6. When observed fever without a clear identification of the reasons of its occurrence.
  7. Under unusual occurrence of pneumonia in children.

The above reasons may result in the appointment of PCR, which allows you to specify with high accuracy the presence of a virus in the body and stages of infection.

Diagnostic method

There are several diagnostic methods that allow to determine the concentration of the IFA. Typically, this is done by collecting the source material: blood, sputum, swab, urine and so on. Most often the concentration of the IFA determines that of blood. However, for a more accurate result is a combination of diagnostic methods.

The main methods of research at suspicion on presence in the body of the virus can be called:

  1. Collection of biological fluids to clarify what concentrations is immunoglobulin.
  2. PCR method has been recently used practically in all cases of research, as it is the most accurate and fast, but has a number of disadvantages, which determine the distortion of the result in certain situations.
  3. Seeding – a method that has been used for the last few years.

Cytomegalovirus rate of blood is determined solely by the attending physician, as should symptoms. Modern PCR-based selection of cmv igg antibodies in the body. This is due to the fact that the development of antibodies occurs almost immediately after emergence of the virus in the body. The degree of manifestation of symptoms does not influence the results obtained.

It is worth noting the point that during the survey the type of PCR is manifested cytomegalovirus igg even aftertreatments. This is because the herpes virus is not removed from the body. The most accurate figure can be called detection of IgM antibodies, which indicate acute form of the disease. To identify the stage of the disease, a study of PCR is carried out periodically.

The results obtained can talk about the following:

  1. Normal the concentration of antibodies suggests that the body can fight infection.
  2. A bad result may be the absence of antibodies in the body, as this may indicate a significant weakening or disappearance of the immune system.
  3. When exceeding the concentration more than 4 times, we can say that there comes the active phase of the disease.
  4. After the occurrence of the acute form of the disease organism becomes particularly vulnerable to the impact of the considered virus.
Analiz na citomegalovirus rasshifrovka, normalnye pokazateli

Cytomegalovirus analysis during the active phase of the disease should be carried out periodically. Note that anti funds with high efficacy against herpes virus is not.

You can often find a situation where the results do not determine how the virus manifests itself, repeated studies are carried out every 14-20 days. If you have received normal values, then verify the accuracy of the diagnosis is possible by putting a different type of analysis so as to predict the degree of manifestation of the virus in the body is quite difficult.

The essence of the PCR method

As previously noted, a large part of these studies lies in the method of PCR. He is studying DNA and finding in it evidence that the organism is a pathogen. The effectiveness of this method is that cytomegalovirus belongs to the group of DNA-containing infections. For this study, which detects antibodies to cytomegalovirus, taken blood, secretions from the cervix, urethra. Also conducted research related to the determination of the concentration of antibodies in the urine.

To the advantages of the method include:

  • High precision.
  • The collection of samples for research is quite simple.
  • The time needed for tests is only a few hours (not more than a day).

However, there are significant drawbacks:

  1. Decoding the obtained results can do only professionals in this field.
  2. The procedure involves the study of DNA that can be carried out only by using special equipment.
  3. The probability of errors, i.e. the possibility of interference of the "human factor" in the process of obtaining results.
  4. Sampling should be conducted by a specialist, which will eliminate the probability of misstatement.

Analysis of the CMV transcript in the case of DNA research allows to make the preliminary diagnosis. However, in order to be sure in the result, there are also other methods of research

Sowing CMV

Transcript analysis for cytomegalovirus can be performed, and the attending physician in the case study method of sowing. In this case, as the samples can serve as sperm, saliva or blood, amniotic fluid. The features of this method include:

  1. The resulting sample is placed in a special environment.
  2. The environment is chosen so that the microorganism can grow and multiply.
  3. After a certain time to conduct research to identify the forms of the virus.

Significant disadvantages of this method include the fact that to get the result you should wait a very long time. During this time, the probability of transfer of infection from one stage to another. Therefore, in recent years it is used infrequently.

Treatment and prevention

In conclusion the prevention and treatment accordingly. Prevention is the following:

  1. Should abandon casual sex.
  2. You should support the immune system. For this purpose, appointed special complexes, vitamins and minerals, developed a certain diet.
  3. Personal hygiene will also help to protect themselves from the virus.
  4. You cannot use the General washing-up, shaving equipment.
  5. Before eating and after visiting public places should wash their hands.
  6. You need to constantly clean the house when you use antiseptic cleaning agents that will eliminate the probability of occurrence of the pathogen at home.
  7. Proper nutrition also helps to improve the body's resistance to bacteria.
Analiz na citomegalovirus rasshifrovka, normalnye pokazateli

Treatment is more difficult. As previously noted, until the invention of tools that can remove the virus from your body. Typically, treatment involves taking drugs that reduce the manifestation of symptoms. Examples would include antibiotics, which reduce fever, pain relievers to relieve muscle pain. In the case of pregnancy, careful control of the condition of women, as it is impossible to prevent the virus in its active phase. Transmission of the pathogen from mother to fetus or child is not in all cases, butthe probability is quite large. Therefore, it is time passes a survey to identify the problem.