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Helicobacter pylori — the Rules of blood test for detection of Helicobacter

Small, spiral-pathogenic bacterium Helicobacter pylori or Helicobacter pylori, in fact, quite often. Ranks second in infection among the population after the herpes. As Helicobacter pylori, the analysis is conducted only on prescription, to determine its obtained only in poor condition when the bacteria spread through the body. The organism is not sensitive to the acidic environment of the stomach and exposure to many antibiotics, so its treatment is usually complex and prolonged. Indicators in diagnosis as Helicobacter pylori norm, absent. It is individual for each person. In some cases, not be therapy in the presence of chronic pathologies and diseases.

What is Helicobacter pylori

Special danger is caused by the bacteria, which spreads quickly through the body thanks to the special structure, small size, equal to only 3 µm, and flagella. They can be 4-6 pieces. Even protective of the immune system can not affect the microorganism. Under adverse conditions goes from a spiral shape in a spherical form of bacteria cocci. Interacts with the epithelium and the walls of the stomach causes the synthesis of ammonia and neutralize gastric acidity. However, Helicobacter pylori has specific symptoms manifestations:

  1. pain during and after eating,
  2. regular heartburn,
  3. unpleasant smell and a bitter taste in my mouth,
  4. nausea,
  5. mucus in the stool or constipation,
  6. indigestion,
  7. cold, wet limbs,
  8. reduced pressure,
  9. the heart rate is reduced,
  10. the pale color of the skin.

In this case, you must complete examination to establish the exact causes of such violations. Pass on the bacterium Helicobacter blood test is necessary, as well as the presence of protective igg antibodies. Otherwise, possible health complications:

  1. gastritis,
  2. ulcerative lesions of the duodenum,
  3. dysbacteriosis,
  4. atopic dermatitis,
  5. dysentery,
  6. cancer, neoplasms.

Should for any violations of to consult a doctor to the gastroenterologist, who will conduct the necessary inspection, give direction to the diagnosis and begin the proper intensive treatment of the bacterium Helicobacter pylori.

Breath test for Helicobacter pylori

Often use the respiratory test, which involves the study of urease activity of bacteria in the body or the release of gas. To take the breath test offered at the first address of the patient or for monitoring a therapeutic treatment.

The procedure is performed in two ways:

  • flat plastic tube,
  • DKTU.

In these cases, the patient places the device in the oral cavity without touching to the sky. To move during the breath test is prohibited. The first phase of the examination lasts no more than 6 minutes. A break with the admission of the urea solution. The second phase lasts for time 6 minutes. This study is considered complete.

Respiratory urease test for Helicobacter pylori has increased, as the norm is "0". It's the difference between the two phases of the survey. Measured in ppm. Other results indicate the presence of bacteria in the body:

  • Is 1.5 – 3.5. Inactive phase,
  • 3,5 – 5,5. Low activity,
  • To 5.5 – 7. The manifestation of the microorganism,
  • 7 — 15. Vigorous activity,
  • 15 and above. The higher the amount of Helicobacter pylori in the blood.

To make the analysis successful, you can't smoke for 3 hours before, eat after 22.00 the day before, eat legumes, dairy products. Banned antibiotics and alcoholic beverages. Be sure to brush your teeth in the morning.

A blood test for Helicobacter

Not every person prescribed as surveys are more accurate and thorough analysis of the blood for bacteria. For this to be the cause of serious deterioration of health in the form of ulcerative lesions, gastritis, disorders of the digestive system, gastroenterologist suspicions on microorganisms:

  • the lowering of the immune system,
  • genetic predisposition to diseases of the gastrointestinal tract,
  • the infection of one member of the family,
  • prevention,
  • evaluation of treatment.

Any visitor to the clinic can be screened voluntarily and on request, to the direction of a specialist.

ELISA blood test for the presence of Helicobacter pylori

The study using special staining of enzymes for the determination of titers or concentrations of IgG antibodies to Helicobacter pylori. Immunoassay blood test is carried out usingclasses A, M and G.

These indicators of immunoglobulins and indicate the number of pathogenic microorganisms:

  • IgG. Manifest themselves at an early stage of infection. 3-4 weeks. The increased number of credits, warns of protracted long life pylori in the body,
  • IgM. The presence of bacteria on the mucosa. Primary penetration.

Often observed false positive and false negative. This is due to the incubation period of the disease. More than 50% of all people who were treated and got rid of the microorganisms, for a long time can show its presence.

Decoding, when the blood test shows normal immunoglobulins, the next:

  1. A is less than 0.9 U/ml,
  2. G is less than 0.9 U/ml,
  3. M less than 30 U/ml.

When raising any indicator, the transcript has other values:

  • IgG. The early period corresponds to 3-4 weeks of infection,
  • IgM. If other antibodies are not, then the result is negative,
  • IgA. Active acute phase.

The rate of presence of inflammatory process and infection is 30 to IgG, IgA. If it is not revealed in the results of the IgA, it is necessary to repeat the test. With increased indices of IgG, IgA, IgM, there is a danger of exacerbation of the infection.

PCR for diagnosis of Helicobacter pylori

Another method, and it is not a study of serum and full blood count and the presence of DNA of foreign bacteria, with subsequent study and comparison with previously obtained samples. Used less taking other materials: feces, urine, saliva. Biopsy.
Often taken on the analysis of feces for Helicobacter. The success of diagnostics is estimated at 93%. But the recovery of patients the bacterial DNA can still be kept for long in the material samples. The blood test also shows dead cells alien microorganism.

A positive response indicates the presence of Helicobacter pylori, a negative or absence. Also often found about the positive and negative result. In this case, PCR analysis of blood or sampling of the material is repeated again.

Express test for Helicobacter pylori

There is an instant definition of bacterial infection Helicobacter. It is small, containing a coloring enzyme test strip. Resembles a respiratory analysis. Ease of use is to independently determine the acute course of the disease. Simple and decoding analysis:

  1. "+++". For the first 60 minutes after the test. Indicates inflammation and aggravation,
  2. "++". The manifestation observed after 2-3 hours. A small degree of contamination,
  3. the "+". The figure slightly turned in within 24 hours. A small presence of microorganisms.

The initial color of the test – orange. Gradually with the passage of the strip should change to a crimson hue. In the absence of changes of the palette – the test was negative.

A biopsy for Helicobacter pylori

Is a cytological laboratory examination of material taken for examination. To obtain the sample used in the method of gastroscopy (EGD) with a special probe for specimen collection. The rules of the biopsy:

  • the morning on an empty stomach,
  • the end of antibiotics,
  • eliminate drink and food the day before. 10 hours before sampling.

This study is useful because at the same time have the opportunity to observe changes in the digestive system visually and conduct the analysis. Decoding biopsy simple:

  • Helicobacter pylori Norma – total absence of bacteria,
  • positive result. If the detected at least 1 member of microorganism.

The convenience of this method of diagnosis consists in determining the number of bacteria:

  1. the "+". Up to 20 individuals,
  2. "++". The smear shows about 40 bacteria,
  3. "+++". The sample is crowded with microorganisms.

Sometimes taken material is placed under the microscope. In acute inflammation, all animals are rendered.

Treatment of the bacterium Helicobacter pylori

Identify in the body harmful bacteria causing complications such as gastritis, ulcerative lesions, and lesions in duodenum or stomach, there is a need of search intensive treatment. It involves the use of not only antibiotics, but also various chemotherapeutic agents. Also commonly used drugs against bacteria and to decrease the production of gastric juice. Self getting rid of microorganisms impossible. Only an experienced gastroenterologist can retrieve the correct schema recovery:

  • initial. Involves the use of 2 antibiotics and 1 funds to reduce the secretion of gastric juice,
  • second. Antibacterials – 2 assignments, 1 – against secret release the juice from the stomach, 1 drug bismuth.

There is another scheme of treatment. Used when lack of sensitivity in bacteria responding to antibiotics and two courses of previous therapy. The majority of cases. The most common tools to fight against Helicobacter pylori:

  • «Tetracycline.» Suppresses the intestinal microflora, inhibits bacteria. Daily dosage of 0.25 – 0.5 grams 4 times. It is possible to increase the reception of the acute 0,5-1 gram every 12 hours,
  • "Flemoksin". At low flow prescribed daily admission – on 500-750 mg 2 times. When complications daily admission – 0.75-1 gram 3time's.
  • «Levofloxacin.» Daily dose — 500 mg 2 times. Duration of therapy is 14 days.

Treatment is under the supervision of a physician. Routinely performed laboratory test on appropriate course of drug therapy. Options include drugs to restore the digestive organs, stomach.